The key difference between centromere and chromomere is that centromere is a constricted region that joins sister chromatids together in a chromosome while chromomere is a linearly arranged bead-like structure present along the length of the chromosome.
A chromosome is a threadlike structure composed of nucleic acids and proteins. They contain the genetic information of an organism. There are several distinct regions in a chromosome, including chromatids, centromere, chromomere and telomere. The centromere is the visible point of constriction in the chromosome. It joins sister chromatids together and is important during the cell division. In contrast, chromomeres are tightly coiled chromatin present along the length of the chromosome. They appear as beads on a string. They carry genes during inheritance.
